Publications

Inferring binding specificities of human transcription factors with the wisdom of crowds

Dec 3, 2025

bioRxiv : the preprint server for biology

Nikita Gryzunov, Dmitry Penzar, Vasilii Kamenets, Valery Vyaltsev, Ivan Kozin, Irina A Eliseeva, Vladimir Nozdrin, Ilya E Vorontsov, Sergey Bushuev, Vadim Strekalovskikh, Arsenii Zinkevich, Gregory Andrews, Matwej Bedarew, Ido Blass, Dmitry Frolov, Iuliia Lariushina, Jill Moore, Yaron Orenstein, German Roev, Danil Salimov, Noam Shimshoviz, Ido Tziony, Zhiping Weng, IBIS Consortium, GRECO-BIT/Codebook Consortium, Philipp Bucher, Bart Deplancke, Oriol Fornes, Jan Grau, Ivo Grosse, Arttu Jolma, Fedor A Kolpakov, Vsevolod J Makeev, Timothy R Hughes, Ivan V Kulakovskiy

Systematic and proactive evaluation of AIRE missense variant effects

Dec 3, 2025

bioRxiv : the preprint server for biology

Anna Axakova, Amund H Berger, Warren van Loggerenberg, Nishka Kishore, Marinella Gebbia, Megan X Ding, Samuel V Douville, Daniel R Tabet, Atina G Cote, Jochen Weile, Stefan Johansson, Eirik Bratland, Frederick P Roth

Systematic Discovery of Pathogen Effector Functions across Human Pathogens and Pathways

Dec 3, 2025

bioRxiv : the preprint server for biology

Tomas Pachano, He Leng, Guillaume Dugied, Travis Tribble, Vincent Loubiere, Felix Rauh, Yeojin Lee, Alexander Schleiffer, Veronika Young, Benjamin Weller, Eleanor A Lyons, Matthew R Hass, Leah C Kottayan, Matthew T Weirauch, Juan I Fuxman Bass, Hayley J Newton, Alexander W Ensminger, Pascal Falter Braun, Daniel Schramek, Alexander Stark, Mikko Taipale

Gene expression profiling reveals two overarching types of ALCL with distinct targetable biology: an LLMPP study

Dec 2, 2025

Blood

Andrew L Feldman, Surendra Dasari, Lisa M Rimsza, David W Scott, Naoki Oishi, Guangzhen Hu, Pedro Farinha, Catalina Amador, Elías Campo, Wing C Chan, James R Cook, Jan Delabie, Kai Fu, Timothy C Greiner, Laura K Hilton, Giorgio Ga Inghirami, Javeed Iqbal, Elaine S Jaffe, Ryan Morin, Sarah L Ondrejka, German Ott, Stefania Pittaluga, Philipp W Raess, Andreas Rosenwald, Kerry J Savage, Graham W Slack, Susan L Slager, Joo Y Song, George Wright, Hao-Wei Wang, Yu Zeng, Tadashi Yoshino, Xiaojun Wu, Ryan A Wilcox, Xueju Wang, Min Shi, Akira Satou, Anamarija M Perry, Roberto Nicolas Miranda, L Jeffrey Jeffrey Medeiros, Matthew J Maurer, Eric Mou, Young Hyeh Ko, Kennosuke Karube, Brad S Kahl, Liuyan Jiang, David L Jaye, Alejandro Gru, Laurence L de Leval, Weina Chen, Jennifer R Chapman, James R Cerhan, Carlos Barrionuevo, Stephen M Ansell, Ahmed Aljudi

Complement-independent pathogenic influences of anti-HMGCR + and anti-SRP + immune-mediated necrotizing myopathy autoantibodies on engineered muscle function

Nov 25, 2025

Skeletal muscle

Heta Lad, Yekaterina Tiper, Ernest Myguel Esteban, Manish K Singh, Alexandrine Mahoudeau, Zhuoye Xie, Berenice Tendrel, Yves Allenbach, Olivier Benveniste, Penney M Gilbert

Differential usage of two, distinct DNA-binding domains regulates tissue-specific occupancy of the pioneer factor Zelda

Nov 24, 2025

bioRxiv : the preprint server for biology

Eliana F Torres-Zelada, Hideyuki Komori, Hsiao-Yun Liu, Elizabeth D Larson, Ally W H Yang, Zoe A Fitzpatrick, Timothy R Hughes, Christine A Rushlow, Cheng-Yu Lee, Melissa M Harrison

The ORB2 RNA-binding protein negatively regulates its target transcripts during the Drosophila maternal-to-zygotic transition via its functionally conserved Zinc-binding 'ZZ' domain

Nov 8, 2025

Genetics

Timothy C H Low, Hua Luo, Chalini Weerasooriya, Zhuyi Wang, Sichun Lin, Angelo Karaiskakis, Stephane Angers, Craig A Smibert, Howard D Lipshitz

Cross-platform motif discovery and benchmarking to explore binding specificities of poorly studied human transcription factors

Nov 7, 2025

Communications biology

Ilya E Vorontsov, Ivan Kozin, Sergey Abramov, Alexandr Boytsov, Arttu Jolma, Mihai Albu, Giovanna Ambrosini, Katerina Faltejskova, Antoni J Gralak, Nikita Gryzunov, Sachi Inukai, Semyon Kolmykov, Pavel Kravchenko, Judith F Kribelbauer-Swietek, Kaitlin U Laverty, Vladimir Nozdrin, Zain M Patel, Dmitry Penzar, Marie-Luise Plescher, Sara E Pour, Rozita Razavi, Ally W H Yang, Ivan Yevshin, Arsenii Zinkevich, Matthew T Weirauch, Philipp Bucher, Bart Deplancke, Oriol Fornes, Jan Grau, Ivo Grosse, Fedor A Kolpakov, Codebook/GRECO-BIT Consortium, Vsevolod J Makeev, Timothy R Hughes, Ivan V Kulakovskiy

Regenerative Healing

Nov 6, 2025

Tissue engineering. Part A

Michael V Sefton, Malcolm King, Alexandra King

The new frontier in understanding human and mammalian brain development

Nov 5, 2025

Nature

Tomasz J Nowakowski, Patricia R Nano, Katherine S Matho, Xiaoyin Chen, Emily K Corrigan, Wubin Ding, Yuan Gao, Matthew Heffel, Jaikishan Jayakumar, Harris S Kaplan, Fae N Kronman, Rothem Kovner, Camiel C A Mannens, Mengyi Song, Marilyn R Steyert, Sridevi Venkatesan, Jenelle L Wallace, Li Wang, Jonathan M Werner, Di Zhang, Guohua Yuan, Guolong Zuo, Seth A Ament, Carlo Colantuoni, Catherine Dulac, Rong Fan, Jesse Gillis, Arnold R Kriegstein, Fenna M Krienen, Yongsoo Kim, Sten Linnarsson, Partha P Mitra, Alex A Pollen, Nenad Sestan, Daniel J Tward, Cindy T J van Velthoven, Zizhen Yao, Aparna Bhaduri, Hongkui Zeng

Publications

Pagination