Recent Publications

A function of TPL/TBL1-type corepressors is to nucleate the assembly of the preinitiation complex

Dec 9, 2024

The Journal of cell biology

Alexander R Leydon, Benjamin Downing, Janet Solano Sanchez, Raphael Loll-Krippleber, Nathan M Belliveau, Ricard A Rodriguez-Mias, Andrew J Bauer, Isabella J Watson, Lena Bae, Judit Villén, Grant W Brown, Jennifer L Nemhauser

A missense variant effect map for the human tumor-suppressor protein CHK2

Dec 6, 2024

American journal of human genetics

Marinella Gebbia, Daniel Zimmerman, Rosanna Jiang, Maria Nguyen, Jochen Weile, Roujia Li, Michelle Gavac, Nishka Kishore, Song Sun, Rick A Boonen, Rayna Hamilton, Jennifer N Dines, Alexander Wahl, Jason Reuter, Britt Johnson, Douglas M Fowler, Fergus J Couch, Haico van Attikum, Frederick P Roth

The WAVE regulatory complex interacts with Boc and is required for Shh-mediated axon guidance

Dec 6, 2024

iScience

Nursen Balekoglu, Jean-Francois Michaud, Rachelle Sauvé, Kehinde S Ayinde, Sichun Lin, Yijun Liu, Daniel A Kramer, Kaiyue Zhang, Anika Steffen, Theresia Stradal, Stephane Angers, Baoyu Chen, Patricia T Yam, Frédéric Charron

N-6-methyladenosine (m6A) promotes the nuclear retention of mRNAs with intact 5' splice site motifs

Dec 3, 2024

Life science alliance

Eliza S Lee, Harrison W Smith, Yifan E Wang, Sean Sj Ihn, Leticia Scalize de Oliveira, Nevraj S Kejiou, Yijing L Liang, Syed Nabeel-Shah, Robert Y Jomphe, Shuye Pu, Jack F Greenblatt, Alexander F Palazzo

Implementation and validation of single-cell genomics experiments in neuroscience

Dec 3, 2024

Nature neuroscience

Marco Colonna, Genevieve Konopka, Shane A Liddelow, Tomasz Nowakowski, Rajeshwar Awatramani, Helen S Bateup, Cathryn R Cadwell, Emre Caglayan, Jerry L Chen, Jesse Gillis, Martin Kampmann, Fenna Krienen, Samuel E Marsh, Michelle Monje, Michael R O'Dea, Rickie Patani, Alex A Pollen, Francisco J Quintana, Marissa Scavuzzo, Matthew Schmitz, Steven A Sloan, Paul J Tesar, Jessica Tollkuhn, Maria Antonietta Tosches, Madeleine E Urbanek, Jonathan M Werner, Omer A Bayraktar, Ozgun Gokce, Naomi Habib

Meta-analysis of single-cell RNA sequencing co-expression in human neural organoids reveals their high variability in recapitulating primary tissue

Dec 2, 2024

PLoS biology

Jonathan M Werner, Jesse Gillis

The co-chaperone DNAJA2 buffers proteasomal degradation of cytosolic proteins with missense mutations

Dec 2, 2024

Journal of cell science

Heather A Baker, Jonathan P Bernardini, Veronika Csizmók, Angel Madero, Shriya Kamat, Hailey Eng, Jessica Lacoste, Faith Au Yeung, Sophie Comyn, Elizabeth Hui, Gaetano Calabrese, Brian Raught, Mikko Taipale, Thibault Mayor

Accurate Spatial Heterogeneity Dissection and Gene Regulation Interpretation for Spatial Transcriptomics using Dual Graph Contrastive Learning

Nov 28, 2024

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Zhuohan Yu, Yuning Yang, Xingjian Chen, Ka-Chun Wong, Zhaolei Zhang, Yuming Zhao, Xiangtao Li

Cross-platform DNA motif discovery and benchmarking to explore binding specificities of poorly studied human transcription factors

Nov 28, 2024

bioRxiv : the preprint server for biology

Ilya E Vorontsov, Ivan Kozin, Sergey Abramov, Alexandr Boytsov, Arttu Jolma, Mihai Albu, Giovanna Ambrosini, Katerina Faltejskova, Antoni J Gralak, Nikita Gryzunov, Sachi Inukai, Semyon Kolmykov, Pavel Kravchenko, Judith F Kribelbauer-Swietek, Kaitlin U Laverty, Vladimir Nozdrin, Zain M Patel, Dmitry Penzar, Marie-Luise Plescher, Sara E Pour, Rozita Razavi, Ally W H Yang, Ivan Yevshin, Arsenii Zinkevich, Matthew T Weirauch, Philipp Bucher, Bart Deplancke, Oriol Fornes, Jan Grau, Ivo Grosse, Fedor A Kolpakov, Codebook/GRECO-BIT Consortium, Vsevolod J Makeev, Timothy R Hughes, Ivan V Kulakovskiy

Extensive binding of uncharacterized human transcription factors to genomic dark matter

Nov 28, 2024

bioRxiv : the preprint server for biology

Rozita Razavi, Ali Fathi, Isaac Yellan, Alexander Brechalov, Kaitlin U Laverty, Arttu Jolma, Aldo Hernandez-Corchado, Hong Zheng, Ally W H Yang, Mihai Albu, Marjan Barazandeh, Chun Hu, Ilya E Vorontsov, Zain M Patel, Codebook Consortium, Ivan V Kulakovskiy, Philipp Bucher, Quaid Morris, Hamed S Najafabadi, Timothy R Hughes

Recent Publications

Pagination