Recent Publications

Pervasive mislocalization of pathogenic coding variants underlying human disorders

Oct 1, 2024

Cell

Jessica Lacoste, Marzieh Haghighi, Shahan Haider, Chloe Reno, Zhen-Yuan Lin, Dmitri Segal, Wesley Wei Qian, Xueting Xiong, Tanisha Teelucksingh, Esteban Miglietta, Hamdah Shafqat-Abbasi, Pearl V Ryder, Rebecca Senft, Beth A Cimini, Ryan R Murray, Chantal Nyirakanani, Tong Hao, Gregory G McClain, Frederick P Roth, Michael A Calderwood, David E Hill, Marc Vidal, S Stephen Yi, Nidhi Sahni, Jian Peng, Anne-Claude Gingras, Shantanu Singh, Anne E Carpenter, Mikko Taipale

TMCO1 is upregulated in breast cancer and regulates the response to pro-apoptotic agents in breast cancer cells

Oct 1, 2024

Cell death discovery

Alice H L Bong, Mélanie Robitaille, Sichun Lin, Amy McCart-Reed, Michael Milevskiy, Stéphane Angers, Sarah J Roberts-Thomson, Gregory R Monteith

Cross-expression analysis reveals patterns of coordinated gene expression in spatial transcriptomics

Sep 30, 2024

bioRxiv : the preprint server for biology

Ameer Sarwar, Mara Rue, Leon French, Helen Cross, Xiaoyin Chen, Jesse Gillis

A rapid in vivo pipeline to identify small molecule inhibitors of amyloid aggregation

Sep 27, 2024

Nature communications

Muntasir Kamal, Jessica Knox, Robert I Horne, Om Shanker Tiwari, Andrew R Burns, Duhyun Han, Davide Levy, Dana Laor Bar-Yosef, Ehud Gazit, Michele Vendruscolo, Peter J Roy

C2H2-zinc-finger transcription factors bind RNA and function in diverse post-transcriptional regulatory processes

Sep 20, 2024

Molecular cell

Syed Nabeel-Shah, Shuye Pu, James D Burns, Ulrich Braunschweig, Nujhat Ahmed, Giovanni L Burke, Hyunmin Lee, Ernest Radovani, Guoqing Zhong, Hua Tang, Edyta Marcon, Zhaolei Zhang, Timothy R Hughes, Benjamin J Blencowe, Jack F Greenblatt

Recruitment of the m⁶A/m6Am demethylase FTO to target RNAs by the telomeric zinc finger protein ZBTB48

Sep 19, 2024

Genome biology

Syed Nabeel-Shah, Shuye Pu, Giovanni L Burke, Nujhat Ahmed, Ulrich Braunschweig, Shaghayegh Farhangmehr, Hyunmin Lee, Mingkun Wu, Zuyao Ni, Hua Tang, Guoqing Zhong, Edyta Marcon, Zhaolei Zhang, Benjamin J Blencowe, Jack F Greenblatt

Constraint-Induced Movement Therapy (CIMT) and Neural Precursor Cell (NPC) Transplantation Synergistically Promote Anatomical and Functional Recovery in a Hypoxic-Ischemic Mouse Model

Sep 14, 2024

International journal of molecular sciences

Prakasham Rumajogee, Svetlana Altamentova, Junyi Li, Nirushan Puvanenthirarajah, Jian Wang, Azam Asgarihafshejani, Derek Van Der Kooy, Michael G Fehlings