Publications

Timer-based proteomic profiling of the ubiquitin-proteasome system reveals a substrate receptor of the GID ubiquitin ligase

May 11, 2021

Molecular cell

Ka-Yiu Edwin Kong, Bernd Fischer, Matthias Meurer, Ilia Kats, Zhaoyan Li, Frank Rühle, Joseph D Barry, Daniel Kirrmaier, Veronika Chevyreva, Bryan-Joseph San Luis, Michael Costanzo, Wolfgang Huber, Brenda J Andrews, Charles Boone, Michael Knop, Anton Khmelinskii

Diagnosing Antibiotic Resistance Using Nucleic Acid Enzymes and Gold Nanoparticles

May 10, 2021

ACS nano

Mohamed A Abdou Mohamed, Hannah N Kozlowski, Jisung Kim, Kyryl Zagorovsky, Melinda Kantor, Jordan J Feld, Samira Mubareka, Tony Mazzulli, Warren C W Chan

NOX4 links metabolic regulation in pancreatic cancer to endoplasmic reticulum redox vulnerability and dependence on PRDX4

May 8, 2021

Science advances

Pallavi Jain, Anna Dvorkin-Gheva, Erik Mollen, Lucie Malbeteau, Michael Xie, Fatima Jessa, Piriththiv Dhavarasa, Stephen Chung, Kevin R Brown, Gun Ho Jang, Parth Vora, Faiyaz Notta, Jason Moffat, David Hedley, Paul C Boutros, Bradly G Wouters, Marianne Koritzinsky

ProTICS reveals prognostic impact of tumor infiltrating immune cells in different molecular subtypes

May 8, 2021

Briefings in bioinformatics

Shuhui Liu, Yupei Zhang, Xuequn Shang, Zhaolei Zhang

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains

May 6, 2021

Molecular cell

Benjamin L Piette, Nader Alerasool, Zhen-Yuan Lin, Jessica Lacoste, Mandy Hiu Yi Lam, Wesley Wei Qian, Stephanie Tran, Brett Larsen, Eric Campos, Jian Peng, Anne-Claude Gingras, Mikko Taipale

Metformin pretreatment rescues olfactory memory associated with subependymal zone neurogenesis in a juvenile model of cranial irradiation

May 5, 2021

Cell reports. Medicine

Daniel Derkach, Tarlan Kehtari, Matthew Renaud, Mohsen Heidari, Nishanth Lakshman, Cindi M Morshead

A survey of the kinome pharmacopeia reveals multiple scaffolds and targets for the development of novel anthelmintics

Apr 29, 2021

Scientific reports

Jessica Knox, Nicolas Joly, Edmond M Linossi, José A Carmona-Negrón, Natalia Jura, Lionel Pintard, William Zuercher, Peter J Roy

Setting molecular traps in yeast for identification of anticancer drug targets

Apr 15, 2021

Proceedings of the National Academy of Sciences of the United States of America

Grant W Brown, Brenda Andrews

Toward the discovery of biological functions associated with the mechanosensor Mtl1p of Saccharomyces cerevisiae via integrative multi-OMICs analysis

Apr 2, 2021

Scientific reports

Nelson Martínez-Matías, Nataliya Chorna, Sahily González-Crespo, Lilliam Villanueva, Ingrid Montes-Rodríguez, Loyda M Melendez-Aponte, Abiel Roche-Lima, Kelvin Carrasquillo-Carrión, Ednalise Santiago-Cartagena, Brian C Rymond, Mohan Babu, Igor Stagljar, José R Rodríguez-Medina

Wnt signaling inhibition confers induced synthetic lethality to PARP inhibitors

Mar 31, 2021

EMBO molecular medicine

Stephane Angers

Publications

Pagination