Publications

Correction: Analysis of an engineered organoid model of pancreatic cancer identifies hypoxia as a contributing factor in determining transcriptional subtypes

Sep 9, 2025

Scientific reports

Natalie Landon-Brace, Simon Latour, Brendan T Innes, Michelle Nurse, Jose L Cadavid, Ileana L Co, Cassidy M Tan, Ferris Nowlan, Sibyl Drissler, Faiyaz Notta, Hartland Warren Jackson, Gary D Bader, Alison P McGuigan

Genetic suppression features ABHD18 as a Barth syndrome therapeutic target

Sep 3, 2025

Nature

Sanna N Masud, Anchal Srivastava, Patricia Mero, Victoria Saba Echezarreta, Eve Anderson, Lennard van Buren, Jiarun Wei, David Thomson Taylor, Adrian Granda Farias, Nicholas Mikolajewicz, Angela Shaw, Brandon M Murareanu, Michelle Lohbihler, Olivia Sniezek Carney, Simon van Heeringen, Linda Clijsters, Olga Sizova, Jeroen van Ameijde, Freya Nye, Andrea Habsid, Lucy Nedyalkova, Laura McDonald, Craig Simpson, Leanne Wybenga-Groot, Kevin R Brown, Nhi Nho, Radu M Suciu, Katherine Chan, Amy H Y Tong, Frédéric M Vaz, Bastiaan Evers, Robert Lesurf, Tanya Papaz, Lauryl M J Nutter, Stephanie Protze, Maximilian Billmann, Michael Costanzo, Brenda J Andrews, Chad L Myers, Seema Mital, Hilary Vernon, Thijn R Brummelkamp, Charles Boone, Ian C Scott, Micah J Niphakis, Douglas Strathdee, Sebastian M B Nijman, Vincent A Blomen, Jason Moffat

Creating an atlas of variant effects to resolve variants of uncertain significance and guide cardiovascular medicine

Sep 1, 2025

Nature reviews. Cardiology

Andrew M Glazer, Daniel R Tabet, Victoria N Parikh, Brett M Kroncke, Atina G Cote, Yuta Yamamoto, Qianru Wang, Ayesha Muhammad, Megan C Lancaster, Matthew J O'Neill, Jochen Weile, Tao Yang, Calum A Macrae, Euan A Ashley, Frederick P Roth, Dan M Roden

HLA Ligand Atlas DIA: extending the benign immunopeptidomics resource with increased sensitivity through data-independent acquisition mass spectrometry

Aug 31, 2025

Journal for immunotherapy of cancer

Leon Bichmann, Ana Marcu, Daniel Johannes Kowalewski, Lena Katharina Freudenmann, Linus Backert, Lena Mühlenbruch, Maren Lübke, Philipp Wagner, Tobias Engler, Sabine Matovina, Mathias Hauri-Hohl, Roland Martin, Holger Moch, Luca Regli, Michael Weller, Markus W Löffler, Juliane S Walz, Oliver Kohlbacher, Hannes Röst, Hans-Georg Rammensee, Marian C Neidert

Integrative High-Throughput RNAi Screening Identifies BRSK1, STK32C and STK40 as Novel Activators of YAP/TAZ

Aug 28, 2025

International journal of molecular sciences

Mandeep K Gill, Siyuan Song, Tania Christova, Liliana Attisano

Gene-set enrichment analysis and visualization on the web using EnrichmentMap:RNASeq

Aug 27, 2025

Bioinformatics advances

Max Franz, Christian T Lopes, Mike Kucera, Veronique Voisin, Ruth Isserlin, Gary D Bader

Large-scale single-cell profiling of stem cells identifies redundant regulators of shoot development and yield trait variation

Aug 27, 2025

Developmental cell

Xiaosa Xu, Michael Passalacqua, Brian Rice, Edgar Demesa-Arevalo, Mikiko Kojima, Yumiko Takebayashi, Xingyao Yu, Benjamin Harris, Yuchen Liu, Andrea Gallavotti, Hitoshi Sakakibara, Jesse Gillis, David Jackson

iPSC-derived cerebral organoids reveal mitochondrial, inflammatory and neuronal vulnerabilities in bipolar disorder

Aug 25, 2025

Translational psychiatry

Dana El Soufi El Sabbagh, Alencar Kolinski Machado, Lauren Pappis, Erika Leigh Beroncal, Delphine Ji, George Nader, Prathyusha Ravi Chander, Jaehyoung Choi, Angela Duong, Hyunjin Jeong, Bruna Panizzutti, Chiara Cristina Bortolasci, Andrea Szatmari, Peter Carlen, Margaret Hahn, Liliana Attisano, Michael Berk, Ken Walder, Ana Cristina Andreazza

Claudin-1 is a mediator and therapeutic target in primary sclerosing cholangitis

Aug 22, 2025

Journal of hepatology

Fabio Del Zompo, Emilie Crouchet, Tessa Ostyn, Zeina Nehme, Mélissa Messé, Frank Juehling, Romain Désert, Angelica T Vieira, Julien Moehlin, Diana Nakib, Tallulah Andrews, Catia Perciani, Sai Chung, Gary Bader, Ian McGilvray, Chiara Caime, Miki Scaravaglio, Marco Carbone, Pietro Invernizzi, Sheraz Yaqub, Trine Folseraas, Tom H Karlsen, Gautam Shankar, Mark Primeaux, Punita Dhawan, Jesus M Banales, Natascha Roehlen, Roberto Iacone, Geoffrey Teixeira, Mathias Heikenwälder, Laurent Mailly, Sonya MacParland, Tania Roskams, Olivier Govaere, Catherine Schuster, Thomas F Baumert

UPR deficiency leads to poor growth, aneuploidy, and a trade-off between ER and general proteostasis in yeast

Aug 22, 2025

Genes & development

Constantine Bartolutti, Allison J Kim, Yanzhe Ma, Thiago P Fernandes, Charles Boone, Marko Jovanovic, Gloria A Brar

Publications

Pagination