donnelly centre building

Advancing discovery, medicine and health

Donnelly Centre is a global research hub where scientists from diverse fields explore the power of genomic technology to advance discovery, medicine and health.
map of genetic interactions
Michael Costanzo
A global map of genetic interactions showing how thousands of genes work together to sustain cellular fitness.
Nov 1, 2024
A team led by researchers at the University of Toronto has discovered that a group of cells located in the skin and other areas of the body, called neural crest stem cells, are the source of reprogrammed neurons found by other researchers.
Oct 25, 2024
An international team led by researchers at the University of Toronto has developed an efficient and robust system, using the C. elegans nematode, to screen for compounds that can stop the growth of amyloid proteins. Through their own screen of over 2,500 compounds, the team found 40 that demonstrate the ability to inhibit amyloid formation.
Oct 22, 2024
An international team led by researchers at the University of Toronto and the Broad Institute of MIT and Harvard has assembled the first large-scale, publicly available map to show the impact of mutations on where proteins end up in the cell.