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Advancing discovery, medicine and health

The Donnelly Centre is a global research hub where scientists from diverse fields explore the power of genomic technology to advance discovery, medicine and health.
May 27, 2026
U of T researchers have shown that cell receptor clustering activates the Wnt signalling pathway, a step towards improving disease interventions.
May 25, 2026
The study used the Stagljar Lab-designed Mammalian Membrane Two-Hybrid technology to reveal how two major drivers in glioblastoma "talk" to each other to promote tumour growth. They also discovered how to disrupt that communication.
May 22, 2026
The Donnelly Centre has awarded Byu Ri Sim the 2026 Jennifer Comyn Graduate Award for Cancer Research. The award will support Sim’s investigation into how the hyperactive pathway signalling behind colorectal cancer cells can be exploited to identify new therapeutic avenues. Sim's dissertation focus is on specific components of the Wnt/β-catenin pathway, which carries signalling mutations in the majority cases of colorectal cancer.