Publications

Immunomodulation With Local, Sustained Delivery of Pituitary Adenylate Cyclase Activating Polypeptide Results in Improved Functional Recovery in Stroke-Injured Mice

Jul 11, 2025

Advanced healthcare materials

Eric Ho, David Xinzheyang Li, Hong Cui, Dania Akbar, Ricky Siu, Cindi M Morshead, David Chatenet, Molly S Shoichet

Analysis of an engineered organoid model of pancreatic cancer identifies hypoxia as a contributing factor in determining transcriptional subtypes

Jul 3, 2025

Scientific reports

Natalie Landon-Brace, Simon Latour, Brendan T Innes, Michelle Nurse, Jose L Cadavid, Ileana L Co, Cassidy M Tan, Ferris Nowlan, Sibil Drissler, Faiyaz Notta, Hartland Warren Jackson, Gary D Bader, Alison P McGuigan

A genome-wide in vivo CRISPR activation screen identifies BACE1 as a therapeutic vulnerability of lung cancer brain metastasis

Jul 2, 2025

Science translational medicine

Shawn C Chafe, Kui Zhai, Nikoo Aghaei, Petar Miletic, Zhi Huang, Kevin R Brown, Daniel Mobilio, Daniel Young, Yujin Suk, Shan Grewal, Dillon McKenna, Zahra Alizada, Agata M Kieliszek, Fred C Lam, Laura Escudero, Qian Huang, Ariana Huebner, Jack Lu, Patrick Ang, Alisha Anand, Stefan Custers, Erika Apel, Sarah Slassi, Benjamin Brakel, Jongmyung Kim, James K C Liu, Blessing Iquo Bassey-Archibong, Rober Abdo, Yaron Shargall, Jian-Qiang Lu, Jean-Claude Cutz, Qi Zhang, Shawn Shun-Cheng Li, Chitra Venugopal, Robert E Hynds, Antoine Dufour, Jason Moffat, Charles Swanton, Shideng Bao, Sheila K Singh

Colistin enhances caspofungin antifungal efficacy against Aspergillus fumigatus by modulating calcium homeostasis and stress responses

Jul 1, 2025

Nature communications

Laura Garcia Carnero, Xingyue Li, Patrícia Alves de Castro, Camila Figueiredo Pinzan, Jonatas Erick Maimoni Campanella, Iran Malavazi, Mami Yoshimura, Luis Alberto Vega Isuhuaylas, Yoko Yashiroda, Charles Boone, Nir Osherov, Sara Fallah, Taylor Davie, Nicole Robbins, Leah Cowen, Ling Lu, Thaila Fernanda Dos Reis, Gustavo H Goldman

Single-cell imaging of protein dynamics of paralogs reveals sources of gene retention

Jun 30, 2025

iScience

Rohan Dandage, Mikhail Papkov, Brittany M Greco, Vanessa Pereira, Dmytro Fishman, Helena Friesen, Kyle Wang, Erin B Styles, Oren Kraus, Benjamin Grys, Gerardo Zapata, Francois Lefebvre, Guillaume Bourque, Charles Boone, Brenda J Andrews, Leopold Parts, Elena Kuzmin

Phenotypic screens for SIRPA expression reveal RAB21 as a general regulator of macrophage surface identity

Jun 28, 2025

Cell reports

Adrian Granda Farias, Brian Feng, Shahbaz Khan, Wayne Ngo, Jamie L Y Wu, Magali Aguilera-Uribe, Shan Grewal, Patricia Mero, Sheila K Singh, Thomas Kislinger, Warren C W Chan, Jason Moffat

A Predictive Tool for Ability to Remain at Home After Cancer Surgery in Older Adults

Jun 25, 2025

JAMA surgery

Julie Hallet, Alyson L Mahar, Wing C Chan, Daniel I McIsaac, Natalie Coburn, Anna Gombay, Matthew Guttman, Barbara Haas, Amy Hsu, Recovery After Surgical Therapy for Older Adults Research—Cancer (RESTORE-Cancer) Group

Targeting synthetic lethality between non-homologous end joining and radiation in very-high-risk medulloblastoma

Jun 25, 2025

Cell reports. Medicine

Alexandria DeCarlo, Graham MacLeod, Carolina Fernandes da Silva, Li Qing Shen, Julija Povilaikaite, Madeline Deane, Lucas Aragao, Mariska Sie, Deborah Termini, Jonathan Magee, Brian Gudenas, Sneha Sukumaran, Frederic Charron, Richard Marcellus, Rima Al-Awar, Ahmed Aman, Denis Reynaud, Amarine Trolat, Leanne Wybenga-Groot, Uri Tabori, Carolina Nör, Shane M Harding, Michael F Moran, Paul A Northcott, Peter Dirks, Stephane Angers, Vijay Ramaswamy

CRISPR-Cas9-Guided Genetic Manipulation of Patient-Derived Brain Tumor Cells

Jun 24, 2025

Methods in molecular biology (Clifton, N.J.)

Yujin Suk, Erika Apel, Stefan Custers, Petar Miletic, Kui Zhai, Chirayu Chokshi, Chitra Venugopal, Jason Moffat, Sheila K Singh

Line-scan imaging for real-time phenotypic screening of C. elegans

Jun 17, 2025

The Review of scientific instruments

Aaron Au, Maximiliano Giuliani, Sean Harrington, Peter Roy, Christopher M Yip

Publications

Pagination