Temerty Faculty of Medicine
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Recent Publications

The CDK12 inhibitor SR-4835 functions as a molecular glue that promotes cyclin K degradation in melanoma

Dec 16, 2023
Cell death discovery
Thibault Houles, Jonathan Boucher, Geneviève Lavoie, Graham MacLeod, Sichun Lin, Stephane Angers, Philippe P Roux

Adversarial training improves model interpretability in single-cell RNA-seq analysis

Dec 15, 2023
Bioinformatics advances
Mehrshad Sadria, Anita Layton, Gary D Bader

Digital microfluidics as an emerging tool for bacterial protocols

Dec 15, 2023
SLAS discovery : advancing life sciences R & D
Carine R Nemr, Alexandros A Sklavounos, Aaron R Wheeler, Shana O Kelley

Engineered In Vitro Tumor Model Recapitulates Molecular Signatures of Invasion in Glioblastoma

Dec 13, 2023
ACS materials Au
Laura J Smith, Arianna Skirzynska, Allysia A Chin, Amy E Arnold, Michelle Kushida, Peter B Dirks, Molly S Shoichet

Encapsulation of Caenorhabditis elegans in Water-in-Water Microdroplets to Study the Worm Viability: Alternative Avenue to Manipulate Microdroplet Environment

Dec 8, 2023
ACS applied materials & interfaces
Sinthuran Jegatheeswaran, June H Tan, Andrew G Fraser, Dae Kun Hwang

Systematic analysis of alternative exon-dependent interactome remodeling reveals multitasking functions of gene regulatory factors

Dec 8, 2023
Molecular cell
Jonathan F Roth, Ulrich Braunschweig, Mingkun Wu, Jack Daiyang Li, Zhen-Yuan Lin, Brett Larsen, Robert J Weatheritt, Anne-Claude Gingras, Benjamin J Blencowe

Aspects of the alternative host response to methacrylic acid containing biomaterials

Dec 6, 2023
Journal of biomedical materials research. Part A
Krystal Ortaleza, So-Yoon Won, Sean M Kinney, Michael V Sefton

CRISPR Screening in Tandem with Targeted mtDNA Damage Reveals WRNIP1 Essentiality

Dec 6, 2023
ACS chemical biology
Tanja Sack, Piriththiv Dhavarasa, Daniel Szames, Siobhan O'Brien, Stephane Angers, Shana O Kelley

Single-cell imaging of protein dynamics of paralogs reveals mechanisms of gene retention

Dec 4, 2023
bioRxiv : the preprint server for biology
Rohan Dandage, Mikhail Papkov, Brittany M Greco, Dmytro Fishman, Helena Friesen, Kyle Wang, Erin Styles, Oren Kraus, Benjamin Grys, Charles Boone, Brenda Andrews, Leopold Parts, Elena Kuzmin

Author Correction: Discovery of an exosite on the SOCS2-SH2 domain that enhances SH2 binding to phosphorylated ligands

Dec 1, 2023
Nature communications
Edmond M Linossi, Kunlun Li, Gianluca Veggiani, Cyrus Tan, Farhad Dehkhoda, Colin Hockings, Dale J Calleja, Narelle Keating, Rebecca Feltham, Andrew J Brooks, Shawn S Li, Sachdev S Sidhu, Jeffrey J Babon, Nadia J Kershaw, Sandra E Nicholson

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