Dec 31, 2024

The mechanisms of electrical neuromodulation

The Journal of physiology
Gustavo Balbinot, Matija Milosevic, Cindi M Morshead, Stephanie N Iwasa, Jose Zariffa, Luka Milosevic, Taufik A Valiante, Joaquín Andrés Hoffer, Milos R Popovic
The central and peripheral nervous systems are specialized to conduct electrical currents that underlie behaviour. When this multidimensional electrical system is disrupted by degeneration, damage, or disuse, externally applied electrical currents may act to modulate neural structures and provide therapeutic benefit. The administration of electrical stimulation can exert precise and multi-faceted effects at cellular, circuit and systems levels to restore or enhance the functionality of the...