Publications

Systematic and proactive evaluation of AIRE missense variant effects

Aug 6, 2026

American journal of human genetics

Anna Axakova, Amund H Berger, Warren van Loggerenberg, Nishka Kishore, Marinella Gebbia, Megan X Ding, Samuel V Douville, Daniel R Tabet, Atina G Cote, Jochen Weile, Stefan Johansson, Eirik Bratland, Frederick P Roth

An expanded codebook of human transcription factor DNA-binding specificity

Aug 5, 2026

Nature

Arttu Jolma, Kaitlin U Laverty, Ali Fathi, Ally W H Yang, Isaac Yellan, Ilya E Vorontsov, Antoni J Gralak, Judith F Kribelbauer-Swietek, Sachi Inukai, Rozita Razavi, Mihai Albu, Alexander Brechalov, Zain M Patel, Vladimir Nozdrin, Georgy Meshcheryakov, Andrey Buyan, Ivan Kozin, Sergey Abramov, Alexandr Boytsov, Codebook Consortium, Quaid Morris, Matthew T Weirauch, Oriol Fornes, Vsevolod J Makeev, Jan Grau, Ivo Grosse, Philipp Bucher, Bart Deplancke, Ivan V Kulakovskiy, Timothy R Hughes

Extensive binding of poorly characterized human transcription factors to genomic dark matter

Aug 5, 2026

Nature communications

Rozita Razavi, Ali Fathi, Isaac Yellan, Alexander Brechalov, Kaitlin U Laverty, Arttu Jolma, Aldo Hernandez-Corchado, Hong Zheng, Ally W H Yang, Mihai Albu, Marjan Barazandeh, Chun Hu, Ilya E Vorontsov, Zain M Patel, Codebook Consortium, Ivan V Kulakovskiy, Philipp Bucher, Quaid Morris, Hamed S Najafabadi, Timothy R Hughes

GHT-SELEX demonstrates unexpectedly high intrinsic sequence specificity and complex DNA binding of many human transcription factors

Aug 5, 2026

Nature methods

Arttu Jolma, Aldo Hernandez-Corchado, Ally W H Yang, Ali Fathi, Kaitlin U Laverty, Alexander Brechalov, Rozita Razavi, Mihai Albu, Hong Zheng, Codebook Consortium, Ivan V Kulakovskiy, Hamed S Najafabadi, Timothy R Hughes

Identification of methylation-sensitive human transcription factors using meSMiLE-seq

Aug 5, 2026

Nature communications

Antoni J Gralak, Katerina Faltejskova, Ally W H Yang, Clemence Steiner, Julie Russeil, Nadia Grenningloh, Sachi Inukai, Mustafa Demir, Riccardo Dainese, Cooper Owen, Eugenia V Pankevich, Codebook/GRECO-BIT Consortium, Timothy R Hughes, Ivan V Kulakovskiy, Judith F Kribelbauer-Swietek, Guido van Mierlo, Bart Deplancke

On-demand microfluidic encapsulation of Caenorhabditis elegans in hydrogel for long-term observation via AI detection

Jul 30, 2026

Lab on a chip

Sinthuran Jegatheeswaran, Teo Mesrkhani, Wei Liu, Mohammad Kashif, June H Tan, Basel A Khader, Elodie Lugez, Andrew G Fraser, Dae Kun Hwang

A consensus atlas of human brain development defines cell type-specific maturation trajectories across the lifespan

Jul 29, 2026

bioRxiv : the preprint server for biology

Sridevi Venkatesan, Patricia Nano, Jonathan Werner, Sonia Malaiya, Brian Herb, Yuan Gao, Li Wang, Aparna Bhaduri, Tomasz J Nowakowski, Carlo Colantuoni, Seth A Ament, Jesse Gillis

The Nematicide Tioxazafen Disrupts Proteasome Function via Cytochrome P450 Bioactivation

Jul 29, 2026

bioRxiv : the preprint server for biology

Lucia Chen, Kaiden Thompson, Muntasir Kamal, Kateryna Sihuta, Irini Topalidou, Andrew R Burns, Nazli H Farshour, Brittany Cooke, Jessica Knox, Yanqing Jiang, Modhar Al Qasser, Ermira Shuteriqi, Matej Usaj, Justin Ching, Arthur Flaget, Michael Costanzo, Guihong Tan, Jessica Lacoste, Mark Lautens, Brenda Andrews, Charles Boone, Mikko Taipale, Nicolas J Lehrbach, Peter J Roy

A genome-wide functional analysis of conserved intronic regions reveals essential roles for speckle-associated retained introns

Jul 20, 2026

Cell reports

Shaghayegh Farhangmehr, Ulrich Braunschweig, Mingkun Wu, Syed Nabeel-Shah, Kevin R Brown, Jacob L Fine, Jason Moffat, Benjamin J Blencowe

Functional characterization of obesity using advanced 3D in vitro adipose tissue models

Jul 20, 2026

Biomaterials

Vera M Pieters, Kyle S Nguyen, Penney M Gilbert, Alison P McGuigan

Publications

Pagination