Discovery Genomics
Donnelly Centre Research Themes
Our faculty have made significant breakthroughs in functional genomics, proteomics and metabolomics, forming a strong foundation for biomedical research. We are pioneers in high-throughput methods that advance our understanding of gene function. Our ongoing work aims to make the human genome more accessible and easier to interpret, helping to reveal how cells and tissues function and guiding drug discovery.
Discovery Genomics News
Aug 5, 2026
A global collaboration spanning eight years has concluded with the creation of the Codebook: an enormous database comprised of over 4,800 experiments that has illuminated how transcription factors influence human gene regulation.
Jun 18, 2026
When researchers published the full genome sequence of the budding yeast Saccharomyces cerevisiae in 1996, the community raced to create mutants for a systematic interrogation of each gene’s role. Researchers Brenda Andrews and Charlie Boone saw the same finish line: a complete, global genetic interaction network map.
Jun 2, 2026
When considering regions of genomes that encode proteins, human DNA is approximately 99% identical to that of chimpanzees. But genetic code similarity does not tell the full evolutionary story. A new study by Blencowe Lab researchers has illuminated a potentially frequent mechanism that generates evolutionary divergence between primate species.
May 25, 2026
The study used the Stagljar Lab-designed Mammalian Membrane Two-Hybrid technology to reveal how two major drivers in glioblastoma "talk" to each other to promote tumour growth. They also discovered how to disrupt that communication.