Genome-wide CRISPR-Cas9 Interrogation of Splicing Networks Reveals a Mechanism for Recognition of Autism-Misregulated Neuronal Microexons. Mol Cell 2018 Nov 02.
Single Cell RNA Sequencing of Human Liver Reveals Distinct Intrahepatic Macrophage Populations. Nat Comms 2018 Oct 22.
Efficient and Accurate Quantitative Profiling of Alternative Splicing Patterns of Any Complexity on a Laptop. Moll Cell 2018 Sep 13.
A Feed Forward Loop Enforces YAP/TAZ Signaling During Tumorigenesis. Nat Comm. 2018 Aug 29.
Stem Cell Bioengineering: Building From Stem Cell Biology. Nat Rev Genet. 2018 Aug 08.
Driving Innovation in Medicine
Discoveries made in basic science are the foundation for all future progress in medicine. Emerging genomic and stem cell technologies hold the promise of personalized treatments that are tailored to patient’s unique genetic makeup and physiology. Through our collaborative approach, the Donnelly Centre is in a position to make breakthrough discoveries in biology and to lead the world in advancing personalized medicine.
Your gift to the Donnelly Centre allows researchers to explore new and innovative ideas that will transform our understanding of biology. It supports discovery that will unearth the cause of human disease, advance diagnosis and disease detection, create personalized therapies, and reverse injury through regenerative medicine.