Patterns of joint involvement in juvenile idiopathic arthritis and prediction of disease course: A prospective study with multilayer non-negative matrix factorization. Plos Med 2019 Feb 25.
Rad5 Recruits Error-Prone DNA Polymerases for Mutagenic Repair of ssDNA Gaps on Undamaged Templates. Mol Cell 2019 Feb 04.
Pathway enrichment analysis and visualization of omics data using g:Profiler, GSEA, Cytoscape and EnrichmentMap. Nat Protoc 2019 Jan 21.
Rationally Designed 3D Hydrogels Model Invasive Lung Diseases Enabling High-Content Drug Screening. Adv Mater 2018 Dec 27.
Genome-wide CRISPR-Cas9 Interrogation of Splicing Networks Reveals a Mechanism for Recognition of Autism-Misregulated Neuronal Microexons. Mol Cell 2018 Nov 02.
Driving Innovation in Medicine
Discoveries made in basic science are the foundation for all future progress in medicine. Emerging genomic and stem cell technologies hold the promise of personalized treatments that are tailored to patient’s unique genetic makeup and physiology. Through our collaborative approach, the Donnelly Centre is in a position to make breakthrough discoveries in biology and to lead the world in advancing personalized medicine.
Your gift to the Donnelly Centre allows researchers to explore new and innovative ideas that will transform our understanding of biology. It supports discovery that will unearth the cause of human disease, advance diagnosis and disease detection, create personalized therapies, and reverse injury through regenerative medicine.